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    建设生物实验室需要保持好哪些原则?

    来源:http://www.sdkjjh.com 日期:2019-01-11 发布人:admin

    1.科学合理准则:传染性和致病性再强的病原微生物,只要它不和人体触摸,感染就不会发生,把病原体围场在必定空间范围内,使之防止暴露在开放的环境中,操作者直接对其操作(如手套、机械手等),在围场内触摸的空气和水体经过处理后排放。在试验室内运用的生物安全柜。在围场(包含安全柜和试验室)内触摸的空气均视为污染的有害物质,把试验室内空气经过HEPA滤器过滤后或其他净化后排放,以保护环境。

    1. Scientific and rational criteria: pathogenic microorganisms with strong infectivity and pathogenicity will not occur as long as they are not touched by human body. The pathogen paddock will be kept in a certain space to prevent exposure to open environment. The operator will operate it directly (such as gloves, manipulators, etc.) and the air and water touched in the paddock will be discharged after treatment. Biosafety cabinet used in laboratory. The air touched in the paddock (including safety cabinet and laboratory) is regarded as harmful substance of pollution. The air in the laboratory is filtered by HEPA filter or other purification to protect the environment.
    2.安全准则:安全是修造试验室的直接目的,建造中全部晦气安全的规划都应撤销,全部与生物安全有冲突的参数规划都应遵守安全的要求。例如:净化要求要遵守安全,运用便利遵守安全,节约遵守安全,人性化遵守安全。
    2. Safety Criteria: Safety is the direct purpose of laboratory construction. All bad safety plans during construction should be cancelled, and all parameter plans that conflict with biological safety should comply with safety requirements. For example, the purification requirements should comply with safety, use convenience to comply with safety, save to comply with safety, and humanize to comply with safety.
    3.规划准则:修造试验室前做好对拟从事的病原微生物和研讨内容的风险评估,必定要有科学、合理的整体构思和概念规划,在此基础上要根据操作过程的梗概进行平面布局工艺规划,然后再进行空调通风和电控等的详细规划。
    3. Planning criteria: To make a risk assessment of pathogenic microorganisms and research contents before building a laboratory, it is necessary to have a scientific and reasonable overall conception and conceptual planning. On this basis, it is necessary to plan the layout process according to the outline of the operation process, and then carry out detailed planning of air conditioning, ventilation and electrical control.
    实验室装修
    4.办理准则:必定要依照国务院发布的《病原微生物试验室生物安全办理条例》进行办理。这个条例对致病微生物的办理准则是:病原微生物是分类办理,试验室是分级办理。
    4. Processing Guidelines: It must be handled in accordance with the Regulations on Biosafety in Pathogenic Microorganism Laboratories promulgated by the State Council. The rules governing pathogenic microorganisms in this regulation are: pathogenic microorganisms are handled by classification and laboratories are handled by classification.
    5. 远离病原准则:建筑试验室是为了研讨致病微生物和高致病微生物,必要的试验必须在试验室内进行。但是,非必要的时候尽可能少触摸病原体或少进试验室。例如,能在半污染区做的不进污染区;能在清洁区做的不进半污染区;进试验室2人能完成不必3人;无关人员不进试验室。运用试验室后应及时净化处理和灭菌,不要存留污物。不必的需要保存的菌(毒)液应送到保藏机构保存。
    5. Avoid pathogenic criteria: Building laboratories is to study pathogenic microorganisms and highly pathogenic microorganisms. The necessary tests must be carried out in laboratories. However, it is not necessary to touch pathogens or enter laboratories as little as possible. For example, non-polluted areas that can be done in semi-polluted areas, non-semi-polluted areas that can be done in clean areas, two people entering the laboratory can complete without three people, and unrelated personnel do not enter the laboratory. After using the laboratory, it is necessary to purify, treat and sterilize in time, and do not retain dirt. Unnecessary bacterial (toxic) liquids that need to be preserved should be sent to storage facilities for preservation.
    6.防备准则:试验室要运用经过生物和物理的检测而且合格的安全柜、排风过滤器和高压蒸汽灭菌器,确保到达零泄漏,经过对试验过程的安全监测,发现问题要及时采取防备和改善办法。有试验室感染的预兆,要及时采取隔离医治办法,以防止呈现二代病例。
    6. Preventive criteria: Laboratories should use biologically and physically tested and qualified safety cabinets, exhaust filters and high-pressure steam sterilizers to ensure zero leakage. After safety monitoring of the test process, timely preventive and improvement measures should be taken to detect problems. If there are signs of laboratory infection, isolation treatment should be taken in time to prevent the occurrence of second-generation cases.
    7.运用准则:试验室建设在确保安全的前提下,应考虑工作过程中活动合理便利的问题。所以在制定方案时应该寻求运用人的定见。
    7. Guidelines for application: On the premise of ensuring safety, the construction of laboratories should consider the issue of reasonable and convenient activities in the process of work. Therefore, in the formulation of the program, we should seek the use of human opinions.
    8. 节约准则:在确保安全的前提下,应提倡节约的准则。确保安全的尺度是国标(GBl9489—2004)。安全性能要可靠,全部都要严格,考究实质,功用完全,合乎要求,但不求豪华。
    8. Economical criteria: On the premise of ensuring safety, we should advocate economical criteria. The measure to ensure safety is the national standard (GBl9489-2004). Safety performance should be reliable, all must be strict, practical, full-featured, meet the requirements, but not luxury.
     

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